ABSTRACT The objective of this study was to evaluate the relationships between preovulatory follicle (POF) and corpus luteum (CL) diameters, and POF and CL vascular perfusion with progesterone production, ovulation, and pregnancy in Nellore cows subjected to timed artificial insemination (TAI). Nellore cows (n = 201) were subjected to ovulation synchronization and later to ultrasound evaluation of POF and CL at the time of insemination (D0) and seven days later (D7), respectively. Females were divided into three categories according to the POF diameter assessed at the time of insemination: small (SF), medium (MF), and large (LF) follicles. The LF group had a greater number and intensity of pixels in the POF ultrasound exam compared with the SF group. The CL flow intensity and progesterone concentration were also higher in the LF group. The SF group showed lower flow intensity and lower ovulation rate compared with the others. When non-pregnant females were compared to pregnant ones, no difference was observed in any of the analyzed variables. The results show for the first time in Nellore cattle the relationship between the size of ovarian structures and blood flow (quantity and intensity) as well as the ability of the CL to produce progesterone. The intensity of the POF pixels proved to be relevant, demonstrating correlations with the size and flow of the CL, which were not found when evaluating only the number of pixels, thus revealing the importance of evaluating complementary characteristics of the flow.

Resumo: A tradução apresenta ao público de língua portuguesa o texto “A história da dialética”, de Herbert Marcuse. Publicado como parte do verbete “Dialética”, na enciclopédia Marxism, Communism, and Western Societies: A Comparative Encyclopaedia (New York: Herder and Herder, 1972), este trabalho fornece uma análise acadêmica relativamente detalhada do “Significado da dialética na Filosofia Antiga”, iniciando em Zenão, nos sofistas e Sócrates, passando por Platão e Aristóteles e concluindo com uma abordagem sobre os estoicos e Plotino; na sequência, volta-se para o horizonte da Filosofia Moderna, a que Marcuse dedica a seção “Significado da dialética em Kant, Fichte e Hegel”; o texto é finalizado com uma análise sobre o “Significado e o alcance da dialética em Marx”, único filósofo privilegiado com uma seção própria. De modo geral, esta publicação revela Marcuse como um estudioso de primeira classe do conceito de dialética e oferece ao leitor uma análise abrangente e extremamente qualificada da história da dialética, no plano filosófico.

Abstract: This translation provides a Portuguese version of “The History of Dialectics”, written by Herbert Marcuse. The original was published as an encyclopedia entry on “Dialectics”, in Marxism, Communism, and Western Societies: A Comparative Encyclopaedia (New York: Herder and Herder, 1972). It starts by presenting a detailed analysis of “The Significance of Dialectics in Ancient Philosophy”, since Zeno, the Sophists and Socrates to Plato, Aristotle, the Stoics and Plotinus. Further on, Marcuse writes a section on “The Significance of Dialectics in Kant, Fichte and Hegel”; he finally concludes with an approach to “The Meaning and Significance of Dialectics in Marx”, the only philosopher who was bestowed with a whole section. Overall, this text exhibits a very comprehensive, qualified analysis of the history of dialectics and reveals Marcuse as a first-rated philosophical scholar in the concept of dialectics.

Abstract Adenocalymma axillarum (K.Schum.) L.G. Lohmann is a liana belonging to the family Bignoniaceae. In traditional medicine, the genus Adenocalymma is used to treat fever, skin ailments, and body, joint, and facial muscle pains, and it is also applied as cosmetic. Biological assays conducted with the A. axillarum crude leaf ethanol extract have indicated leishmanicidal activity and absence of cytotoxicity. This study aimed to analyze the A. axillarum leaf ethanol crude extract by high-performance liquid chromatography-high-resolution mass spectrometry- diode array detector (HPLC-HRMS-DAD) and to evaluate the leishmanicidal and cytotoxic activities of this crude extract, its fractions, and isolated compounds. HPLC-HRMS-DAD analysis of this extract revealed that it consisted mainly of flavonoids, with nine major compounds. Extract purification yielded 4-hydroxy-N-methylproline, 6-β-hydroxyipolamiide, quercetin-3-O-robinobioside, hyperin, isorhamnetin-3-O-robinobioside, and 3’-O-methylhyperin, which were identified by Nuclear Magnetic Resonance. The isolated compounds were inactive against Leishmania amazonensis promastigotes and human lung fibroblast cells.